Research Highlight

Quantitative hemodynamic analysis of cerebral blood flow and neurovascular coupling using optical coherence tomography angiography

Functional hyperemia in the rat cortex was investigated using high-speed optical coherence tomography (OCT) angiography. OCT angiography (OCTA) was performed to image the hemodynamic stimulus-response over a wide field of view. Temporal changes in vessel diameters in different vessel compartments were measured in order to monitor localized hemodynamic changes. This research demonstrates the potential of OCTA for the investigation of neurovascular coupling in small animal models....read more