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Research Highlight
Superfast and Sensitive Optogenetic Module, CRY2clust
A new optogenetic method has been developed to induce rapid and robust protein clustering....read more
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Research Highlight
Systems-level Analyses of Streptomyces Genome Identify Genes for Novel Antibiotics Production
The growing number of antibiotic-resistant bacteria is a substantial global public health concern. Traditional antimicrobial and antibiotic development strategies are no longer effective against the quickly rising resistance to virtually all drugs on the market, and to date there are only a few approved efficient vaccines against the potentially fatal superbacterial infections. To counteract this threat, the genetic potential of Streptomyces species has been explored to produce a diverse array of new antibiotics. Here we show systems-level analyses of multiple genome-wide data sets elucidating the relationship between transcription and translation of the antibiotic-producing bacterium, Streptomyces coelicolor. Our findings offer target genes for a potentially novel route for strain engineering to enhance novel antibiotics production....read more
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Research Highlight
Structure of Huntington’s Disease Protein Unveiled
Currently, Huntington's disease is an inherited neurodegenerative disease with no cure. In this research, the structure of proteins that causes Huntington's disease is revealed providing a structural framework to understand molecular basis of pathogenesis and to develop a means to cure the disease....read more
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Research Highlight
Surfing the Brain with iWEBS
A new technique called iWEBS enables activity monitoring across the entire brain surface using an insertable wrapping electrode array...read more
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Research Highlight
A New Epigenetic Player in Melanoma Tumor Progression and Metastasis
A new study reveals how JMJD3, a histone demethylase protein, promotes tumor by regulating methylation status of a specific target gene promoter locus....read more
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