A microfluidic smart blood-typing device operated by finger actuation is reported. The blood-typing results are displayed by means of microfluidic channels with the letter and the symbol of the corresponding blood type. To facilitate the mixing of blood and reagents in the device, the two sample inlets are connected to a single actuation chamber. According to the agglutination aspect in the mixture, the fluids are directed to both microslit filter channels and bypass channels, or only to bypass channels. With this device, blood typing was successfully performed by seven button pushes, using less than 10 μL of blood within 30 s....read more
An innovative bio-imaging technique enables real-time in vivo visualization of pulmonary microcirculation, leading to the discovery of active cluster formation of neutrophils inside the microvasculature during the pathogenesis of acute lung injury in sepsis...read more