The growing number of antibiotic-resistant bacteria is a substantial global public health concern. Traditional antimicrobial and antibiotic development strategies are no longer effective against the quickly rising resistance to virtually all drugs on the market, and to date there are only a few approved efficient vaccines against the potentially fatal superbacterial infections. To counteract this threat, the genetic potential of Streptomyces species has been explored to produce a diverse array of new antibiotics. Here we show systems-level analyses of multiple genome-wide data sets elucidating the relationship between transcription and translation of the antibiotic-producing bacterium, Streptomyces coelicolor. Our findings offer target genes for a potentially novel route for strain engineering to enhance novel antibiotics production....read more
A new principle of traffic signal operation enhances mobility and diminishes CO2 emissions in the congested roadway network....read more
KAIST researchers have developed a wall-climbing scout drone that can fight fires in high-rises, find the source of the fires, and locate people trapped inside....read more
A first-principles computational investigation sheds light on the atomistic origins of the excellent electrocatalytic activity of edge-selenated graphene nanoplatelets as dye-sensitized solar cell counter electrodes....read more
A new method called wavefront shaping optical coherence tomography (WS-OCT) enables in vivo deep tissue imaging of a mouse....read more
A Saudi Aramco-KAIST CO2 Management Center project led by Professor Sang Woo Han (Chemistry, KAIST) develops efficient CO2 conversion catalysts to produce high value commodity chemicals....read more
Recently, supercritical CO2 (S-CO2) cycle has been receiving attention as one of the future power cycle technologies because of its compact configuration and high thermal efficiency. Professor Jeong Ik Lee’s laboratory at KAIST has conducted research using the S-CO2 cycle as a bottoming cycle to a gas turbine to generate electricity with CO2 while using less water....read more
Currently, Huntington's disease is an inherited neurodegenerative disease with no cure. In this research, the structure of proteins that causes Huntington's disease is revealed providing a structural framework to understand molecular basis of pathogenesis and to develop a means to cure the disease....read more
A Saudi Aramco-KAIST CO2 Management Center project led by Professor Doh Chang Lee (CBE, KAIST) designs photoelectrochemical cells in which carbon dioxide and water turn into value-added hydrocarbon fuels....read more
A new bio-imaging technique enables a real-time visualization of the live small intestine, leading to the discovery of lacteal contractility and its role for lipid drainage....read more